Which guidelines provide principles on the conduct of clinical trials and communication of results?

The PhRMA Guidelines, developed by the Pharmaceutical Research and Manufacturers of America, specifically address the conduct of clinical trials and emphasize the importance of transparent communication of research results. These guidelines are centered on fostering ethical practices within the pharmaceutical industry, ensuring that trial data is reported responsibly, and that findings are communicated in a manner that supports informed medical decision-making.

The PhRMA guidelines cover various aspects of clinical trials, including the responsibilities of sponsors, the rights of participants, and the importance of publishing trial results, even if they are not favorable. This commitment promotes integrity in research and enhances public trust in clinical findings.

In contrast, the other options focus on different aspects of research or specific populations. The ICMJE Guidelines primarily focus on the standards for authorship and publication ethics, the ISSCR Guidelines are dedicated to stem cell research specifically, and the WHO Guidelines encompass a broader range of health recommendations and protocols but do not specifically target the conduct of clinical trials and their communication in the same focused manner as the PhRMA Guidelines.